Speaking of losing one's livelihood because she came out as trans, check out this post from Buzz Feed News:

But Madden’s optimism was misplaced. Now, more than three years after coming out, Madden says that neither Discovery, nor any other network or production company, has hired her to run another show.
“I never know if [an executive’s] not calling me back because I’m transgender, because she doesn’t have anything for me, or because she no longer works there — you never know,” Madden told BuzzFeed News, describing the often ambiguous nature of show business. “When you work for hire, you serve at the mercy of somebody's whim. The phrase you always hear is, ‘It just didn’t work out.’ And that covers all manners of things.” As showrunners, Madden explained, “Our clients are both the network and the production company.” As the linchpin between the two, they pitch ideas, help TV executives develop shows, and officially get the job when and if the show gets bought.
Onscreen transgender representation in Hollywood is severely lacking; the GLAAD Media Institute found that across broadcast, cable, and streaming television series that aired during the 2017–2018 season, only 17 regular and recurring characters were trans. The statistics aren’t any better for trans people behind the camera, with a few exceptions like Shadi Petosky, who created Amazon’s Danger & Eggs animated series after working for eight years as an animation supervisor on Nick Jr.’s Yo Gabba Gabba! Like most showrunners, Madden had worked steadily in television before running a show. But since she came out as transgender, Madden says the job offers have dried up. "For more, go here. and always remember, keep your friends close and your enemies closer.
Many years ago, in another life, I had a very well paying restaurant job. In fact, my monthly bonus check were enough for me to buy a brand new Porsche Boxster. Even though I knew I would be playing with fire driving it around in my favorite blond wig, I kept thinking you only live once.
One night, I took it to a little lesbian bar when I was cross dressed in my tight jeans and top. I had just settled into my first beer when another female patron walked in and loudly exclaimed "Who is driving that car?" I politely explained I was and of course she then asked for a ride. It was at this point the whole idea became a little dicey. Very simply put, my wig wasn't attached very tight to my head and I was driving with the top down. I had a very real nightmarish idea my wig could come of in front of a stranger and fly into the night.
To make a long story short, my wig stayed where it should have been and the ride was very successful. I was just fortunate no one else asked for a ride.
Sadly, several years later when I lost almost everything else in my life, I lost the car too.