First of all, "HRT" refers to hormone replacement therapy or the taking of hormones of the opposite birth gender, while taking another med to decrease your existing gender hormones.
If it sounds complicated, some time it is and sometimes it isn't, depending many times on your age and health. For example, taking extra estrogen (or a synthetic replacement) has been linked to extra blood clots and other health problems.
So, HRT is not for everyone and should always be administered under the guidance of a physician.
My reason for outlining all of this comes from a comment from Connie: